Company overview:
1910 Genetics is the only company that has built a synergistic,
dual-purpose small and large molecule platform that integrates artificial intelligence (AI),
computation, and biological automation to design drug-like molecules better, faster, and cheaper than traditional approaches.
Based in the Seaport District of Boston, 1910 Genetics is a Series A stage biotechnology startup that was founded in 2018
and is backed by prestigious investors, including M12-Microsoft’s Venture Fund, Sam Altman – the CEO of OpenAI (makers of ChatGPT),
Playground Global, Y Combinator, New Ventures Funds (Scientia Ventures), and many others.
At 1910 Genetics, we first established an understanding of the molecular basis of disease to the granularity at
which the world understands sickle cell anemia. This understanding centers biology as our North Star and drives
our integration of artificial intelligence (AI), computation, and biological automation to accelerate the design
of small molecule and protein therapeutics.
Recent advances in computational technologies have placed historically
“undruggable” targets within therapeutic reach. But at 1910 Genetics,
we often say “Biology is King,” meaning that computational technologies
are only impactful in drug discovery when driven by experimental biology.
Our platforms’ scale and breadth empower us to be therapeutic area-agnostic
with programs ranging from neuroscience and immunology to infectious disease
and oncology, to name a few.
COMPANY OVERVIEW:
Computation is revolutionizing drug discovery. Advances in big chemical data, massive computing power, artificial intelligence, and molecular dynamics simulation are changing the way we develop new drugs. At 1910 Genetics, we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, genetics, data science, and software engineering to develop drugs for previously undruggable targets.
To assist with our goal of expediting drug discovery, 1910 Genetics seeks an Automation Engineer for a hands-on and impactful position within our Biology group. The role will support assay scientists in transitioning validated biochemical and cellular assays onto an automated liquid handling platform. The individual will be solely responsible for working with assay biologists to understand the experiment and develop the protocols for automation on our state-of-the-art Hamilton Vantage liquid handling system. The individual will also be responsible for maintaining Opentrons protocols used in compound management and the creation of assay-ready plates.
In this role you will…
- Troubleshoot existing liquid handling protocols for the Hamilton Venus
- Develop and optimize new liquid handler protocols for biochemical and cellular assays, specifically using Hamilton Venus/Vantage
- Assist scientists with operation of automation platforms
- Track/record problems with the systems for proper troubleshooting
- Implement quality control steps into automated workflows
- Develop ongoing lab-wide training processes and policies
- Train users on new methods and protocols
- Interface with Hamilton representatives to co-ordinate routine maintenance
- Present experimental results to team members and management with recommendations for next steps and improvements
Ideally, you have…
- A B.S./M.S. in Biology or closely related field with an interest in engineering, or a B.S./M.S. in engineering
- 2-4 years’ relevant experience with liquid handlers and biological assay development
- Demonstrated ability to develop and troubleshoot liquid handling methods for biochemical and cell-based assays
- Experience with Tecan or Hamilton liquid handlers, Opentrons experience is a plus
- Experience with designing and implementing quality control systems is a plus
- Experience with developing, troubleshooting, and executing high throughput microtiter plate-based assays, enzyme assays, cell-based assays, etc. is highly desired
- Effective communication skills, ability to work directly with users to understand requirements
- Experience at a high growth biotech startup is preferred
- Proficiency with the Microsoft Office Suite (Excel, Word, PowerPoint, Teams), G-Suite, and lab databases and documentation systems
- Experience with programming languages (Python, C++, R) is a plus
Compensation & benefits
- Extremely generous equity package coupled with competitive salary
- Flexible work schedule including 2 work from home days
- Generous vacation and parental leave
- Healthcare benefits
- Great Colleagues